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In this review, we summarize the current research on the epigenetic mechanisms and molecular biology of CS-induced pulmonary vascular endothelial cell apoptosis in COPD, providing a new research direction for pathogenesis of COPD and a new target for the diagnosis, treatment, and prevention of COPD

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To note, some studies have suggested that individuals with a history of hypertension who used combustible tobacco products exhibited a notable reduction in systolic blood pressure (SBP) and diastolic blood pressure (DBP) when they switched to ENDS [79]